Hypnerotomachia Poliphili, called in English Poliphilo's Strife of Love in a Dream or The Dream of Poliphilus, is a book said to be by Francesco Colonna. It is a famous example of an incunable. The work was first published in 1499 in Venice by Aldus Manutius. This first edition has an elegant page layout, with refined woodcut illustrations in an Early Renaissance style. Hypnerotomachia Poliphili presents a mysterious arcane allegory in which the main protagonist, Poliphilo, pursues his love, Polia, through a dreamlike landscape. In the end, he is reconciled with her by the "Fountain of Venus".

An incunable or incunabulum is a book, pamphlet, or broadside that was printed in the earliest stages of printing in Europe, up to the year 1500. Incunabula were produced before the printing press became widespread on the continent and are distinct from manuscripts, which are documents written by hand. Some authorities on the history of printing include block books from the same time period as incunabula, whereas others limit the term to works printed using movable type.