The RISC System/6000 (RS/6000) is a family of RISC-based Unix servers, workstations and supercomputers made by IBM in the 1990s. The RS/6000 family replaced the IBM RT PC computer platform in February 1990 and was the first computer line to see the use of IBM's POWER and PowerPC based microprocessors. In October 2000, the RS/6000 brand was retired for POWER-based servers and replaced by the eServer pSeries. Workstations continued under the RS/6000 brand until 2002, when new POWER-based workstations were released under the IntelliStation POWER brand.

PowerPC is a reduced instruction set computer (RISC) instruction set architecture (ISA) created by the 1991 Apple–IBM–Motorola alliance, known as AIM. PowerPC, as an evolving instruction set, has been named Power ISA since 2006, while the old name lives on as a trademark for some implementations of Power Architecture–based processors.