The IBM System/370 (S/370) is a range of IBM mainframe computers announced as the successors to the System/360 family on June 30, 1970. The series mostly maintains backward compatibility with the S/360, allowing an easy migration path for customers; this, plus improved performance, were the dominant themes of the product announcement.

The IBM System/390 is a discontinued mainframe product family implementing ESA/390, the fifth generation of the System/360 instruction set architecture. The first computers to use the ESA/390 were the Enterprise System/9000 (ES/9000) family, which were introduced in 1990. These were followed by the 9672, Multiprise, and Integrated Server families of System/390 in 1994–1999, using CMOS microprocessors. The ESA/390 succeeded ESA/370, used in the Enhanced 3090 and 4381 "E" models, and the System/370 architecture last used in the IBM 9370 low-end mainframe. ESA/390 was succeeded by the 64-bit z/Architecture in 2000.