The Institute for Colored Youth was founded in 1837 in Philadelphia, Pennsylvania, United States. It became the first college for African-Americans in the United States, although there were schools that admitted African Americans preceding it. At the time, public policy and certain statutory provisions prohibited the education of blacks in various parts of the nation and slavery was entrenched across the south. It was followed by two other black institutions— Lincoln University in Pennsylvania (1854), and Wilberforce University in Ohio (1856). The second site of the Institute for Colored Youth at Ninth and Bainbridge Streets in Philadelphia was added to the National Register of Historic Places in 1986. It is also known as the Samuel J. Randall School. A three-story, three-bay brick building was built for it in 1865, in the Italianate-style After moving to Cheyney, Pennsylvania in Delaware County, Pennsylvania its name was changed to Cheyney University.

Cheyney University of Pennsylvania is a public historically black university in Cheyney, Pennsylvania. Founded in 1837 as the Institute for Colored Youth, it is the oldest of all historically black colleges and universities (HBCUs) in the United States. It is a member of the Pennsylvania State System of Higher Education and the Thurgood Marshall College Fund. The university offers bachelor's degrees and is accredited by the Middle States Commission on Higher Education.