The InterContinental New York Barclay Hotel is a hotel at 111 East 48th Street, on Lexington Avenue between 48th and 49th Streets, in the Midtown Manhattan neighborhood of New York City. The 14-story hotel, operated by IHG Hotels & Resorts, was designed by Cross and Cross in the Colonial style and contains 702 rooms. The Barclay was one of several large hotels developed around Grand Central Terminal as part of Terminal City.

Cross & Cross (1907–1942) was a New York City-based architectural firm founded by brothers John Walter Cross and Eliot Cross.