Internexin
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Internexin, alpha-internexin, is a Class IV intermediate filament approximately 66 kDa. The protein was originally purified from rat optic nerve and spinal cord. The protein copurifies with other neur
Mixed neuron/glial cultures from p18 rat embryo brain stained with antibody to alpha-internexin which reveals, in red, neuronal processes and cell bodies. Cells were also labelled in green for Coronin 1a, a marker for microglia.
Axon
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An axon is a long slender projection of a nerve cell or neuron found in most animals that typically conducts electrical impulses known as action potentials away from the nerve cell body. The function
Internexin
…Alpha-internexin is a brain and central nervous system filament that is involved in neuronal development and has been suggested to play a role in axonal outgrowth. Gefiltin and xefiltin, homologs of α-internexin in zebrafish and Xenopus laevis, respectively, are highly expressed during retinal growth…
A dissected human brain, showing grey matter and white matter
TEM of a myelinated axon in cross-section
Synaptic connections from an axon
Axon of nine-day-old mouse with growth cone visible