Interstate 17 (I-17) is a north–south Interstate Highway entirely within the US state of Arizona. I-17's southern terminus lies in Phoenix, at I-10/US 60 and its northern terminus is in Flagstaff, at Milton Road north of I-40.

In the U.S. state of Arizona, Interstate 10 (I‑10), the major east–west Interstate Highway in the United States Sun Belt, runs east from California, enters Arizona near the town of Ehrenberg and continues through Phoenix and Tucson and exits at the border with New Mexico near San Simon. The highway also runs through the cities of Casa Grande, Eloy, and Marana. Segments of the highway are referred to as either the Papago Freeway, Inner Loop, or Maricopa Freeway within the Phoenix area and the Pearl Harbor Memorial Highway outside metro Phoenix.