Interstate 390 (I-390) is a 76.06-mile (122.41 km) north–south auxiliary Interstate Highway located entirely within New York in the United States. The southern terminus of the route is at the Southern Tier Expressway in the town of Avoca. Its northern terminus is at I-490 in Gates, just west of Rochester. North of I-490, the expressway continues as NY 390 to the Lake Ontario State Parkway in Greece. I-390 connects to its parent, I-90, in Henrietta, a southern suburb of Rochester. The route is known as the Genesee Expressway from Avoca to I-590 in Brighton, where it becomes part of the Rochester Outer Loop.

Interstate 590 (I-590) is a north–south auxiliary Interstate Highway that serves the immediate southeastern suburbs of the city of Rochester, New York, in the United States. It extends for 5.31 miles (8.55 km) from an interchange with I-390 in Brighton to the Can of Worms, a complex interchange connecting I-590 to I-490 just inside the Rochester city line. I-590 makes up the southeast quadrant of the Rochester Outer Loop, which continues west on I-390 and north past the Can of Worms on New York State Route 590 (NY 590). The highway is a spur route of I-90; the connection between the two is made via both I-390 and I-490.