Interstate 86 (I-86) is an Interstate Highway that extends for 223.39 miles (359.51 km) through northwestern Pennsylvania and the Southern Tier region of New York, in the United States. The highway has two segments: the longer of the two begins at an interchange with I-90 east of Erie, Pennsylvania, and ends just beyond the Chemung-Tioga county line at the Pennsylvania border, while the second extends from I-81 east of Binghamton to New York State Route 79 (NY 79) in Windsor. When projects to upgrade the existing NY 17 to Interstate Highway standards are completed, I-86 will extend from I-90 near Erie to the New York State Thruway (I-87) in Woodbury. The portion in Erie County, Pennsylvania, is known as the Hopkins-Bowser Highway and is signed as such at each end. In New York, the current and future alignment of I-86 is known as the Southern Tier Expressway west of I-81 in Binghamton and the Quickway east of I-81.

The New York State Thruway is a system of controlled-access toll roads spanning 569.83 miles (917.05 km) within the U.S. state of New York. It is operated by the New York State Thruway Authority (NYSTA), a New York State public-benefit corporation. The 496.00-mile (798.23 km) mainline is a freeway that extends from the New York City line at Yonkers to the Pennsylvania state line at Ripley by way of I-87 and I-90 through Albany, Syracuse, and Buffalo. According to the International Bridge, Tunnel and Turnpike Association, the Thruway is the fifth-busiest toll road in the United States. The toll road is also a major route for long distance travelers linking the cities of Toronto and Buffalo with Boston and New York City.