Interstate 75 (I-75) is a part of the Interstate Highway System that runs from the Hialeah–Miami Lakes border, a few miles northwest of Miami, to Sault Ste. Marie in the Upper Peninsula of Michigan. I-75 begins its national northward journey near Miami, running along the western parts of the Miami metropolitan area before traveling westward across Alligator Alley, resuming its northward direction in Naples, running along Florida's Gulf Coast, and passing the cities of Fort Myers, Punta Gorda, Venice, and Sarasota. The freeway passes through the Tampa Bay area before turning inward toward Ocala, Gainesville, and Lake City before leaving the state and entering Georgia. I-75 runs for 471 miles (758 km) in Florida, making it the longest Interstate in the state and also the longest in any state east of the Mississippi River. The Interstate's speed limit is 70 mph (110 km/h) for its entire length in Florida.

Hialeah is a city in Miami-Dade County, Florida, United States. With a population of 223,109 as of the 2020 census, Hialeah is the sixth-largest city in Florida. It is the second largest city by population in the Miami metropolitan area of South Florida, which was home to an estimated 6,198,782 people at the 2018 census. It is located west-northwest of Miami, and is one of a few places in the county—others being Homestead, Miami Beach, Surfside, Bal Harbour, Sunny Isles Beach, and Golden Beach—to have its own street grid numbered separately from the rest of the county.