Interstate 80 (I-80) in the US state of Ohio runs across the northern part of the state. Most of the route is part of the Ohio Turnpike; only an 18.78-mile (30.22 km) stretch is not part of the toll road. That stretch of road is the feeder route to the Keystone Shortway, a shortcut through northern Pennsylvania that provides access to New York City.

The Ohio Turnpike, officially the James W. Shocknessy Ohio Turnpike, is a controlled-access toll road in the U.S. state of Ohio, serving as a primary corridor between Chicago and Pittsburgh. The road runs east–west for 241 miles (388 km) in the northern section of the state, with the western end at the Indiana–Ohio border near Edon where it meets the Indiana Toll Road, and the eastern end at the Ohio–Pennsylvania border near Petersburg, where it meets the Pennsylvania Turnpike. The road is owned and maintained by the Ohio Turnpike and Infrastructure Commission (OTIC), headquartered in Berea.