Interstate 80 (I-80) is a part of the Interstate Highway System that runs from San Francisco, California, to Teaneck, New Jersey. The portion of the highway in the US state of Utah is 197.51 miles (317.86 km) long through the northern part of the state. From west to east, I-80 crosses the state line from Nevada in Tooele County and traverses the Bonneville Salt Flats—which are a part of the larger Great Salt Lake Desert. It continues alongside the Wendover Cut-off—the corridor of the former Victory Highway—US Route 40 (US-40) and the Western Pacific Railroad Feather River Route. After passing the Oquirrh Mountains, I-80 enters the Salt Lake Valley and Salt Lake County. A short portion of the freeway is concurrent with I-15 through Downtown Salt Lake City. At the Spaghetti Bowl, I-80 turns east again into the mouth of Parleys Canyon and Summit County, travels through the mountain range, and intersects the eastern end of I-84 near Echo Reservoir before turning northeast toward the Wyoming border near Evanston. I-80 was built along the corridor of the Lincoln Highway and the Mormon Trail through the Wasatch Range. The easternmost section also follows the historical routes of the first transcontinental railroad and US-30S.

The Dwight D. Eisenhower National System of Interstate and Defense Highways, commonly known as the Interstate Highway System, or the Eisenhower Interstate System, is a network of controlled-access highways that forms part of the National Highway System in the United States. The system extends throughout the contiguous United States and has routes in Hawaii, Alaska, and Puerto Rico.