Isaac Newton was an agriculturalist who became the first United States commissioner of agriculture.

Amanda Almira Newton was a botanical illustrator for the U.S. Department of Agriculture (USDA) who specialized in watercolors of fruit. Her work is now preserved in the USDA's Pomological Watercolor Collection, and she is the second-most prolific contributor to that archive of 7600 paintings, with her work representing roughly one-sixth of the total.