Issaquah Creek is a small stream flowing through the city of Issaquah and nearby communities, in the U.S. state of Washington. Its headwaters are on the slopes of Cougar, Squak, Tiger, and Taylor mountains in the Issaquah Alps. Tributaries of Issaquah Creek include Holder Creek, Carey Creek, Fifteen-mile Creek, McDonald Creek, East Fork Issaquah Creek, and North Fork Issaquah Creek. The creek empties into the south end of Lake Sammamish. The lake's outlet is the Sammamish River, which in turn empties into Lake Washington and ultimately Puget Sound.

Issaquah is a city in King County, Washington, United States. The population was 40,051 at the 2020 census. Located in a valley and bisected by Interstate 90, the city is bordered by the Sammamish Plateau to the north and the "Issaquah Alps" to the south. It is home to the headquarters of the multinational retail company Costco Wholesale Corporation. Issaquah is included in the Seattle metropolitan area.