Joseph William Swain de Graft-Johnson was a Ghanaian engineer, academic and politician. He served as Vice-President of Ghana from 1979 to 1981.

The vice-president of Ghana is the second-highest officer in the Government of Ghana. The vice-president, together with the President of Ghana, is directly elected by the people through popular vote to serve a four-year term in office. The vice-president is the first person in the presidential line of succession, and would ascend to the presidency upon the death, resignation, or removal of the president. The current vice-president is Mahamudu Bawumia, who took office on 7 January 2017, under President Nana Akufo-Addo.