Judenfrei and judenrein are terms of Nazi origin to designate an area that has been "cleansed" of Jews during The Holocaust. While judenfrei refers merely to "freeing" an area of all of its Jewish inhabitants, the term judenrein has the even stronger connotation that any trace of Jewish blood had been removed as an alleged impurity in the minds of the criminal perpetrators. These terms of racial discrimination and racial abuse are intrinsic to Nazi anti-Semitism and were used by the Nazis in Germany before World War II and in occupied countries such as Poland in 1939. Judenfrei describes the local Jewish population having been removed from a town, region, or country by forced evacuation during the Holocaust, though many Jews were hidden by local people. Removal methods included forced re-housing in Nazi ghettos especially in eastern Europe, and forced removal or Resettlement to the East by German troops, often to their deaths. Most Jews were identified from late 1941 by the yellow badge as a result of pressure from Joseph Goebbels and Heinrich Himmler.

The history of the Jews in Germany goes back at least to the year 321 CE, and continued through the Early Middle Ages and High Middle Ages when Jewish immigrants founded the Ashkenazi Jewish community. The community survived under Charlemagne, but suffered during the Crusades. Accusations of well poisoning during the Black Death (1346–53) led to mass slaughter of German Jews, while others fled in large numbers to Poland. The Jewish communities of the cities of Mainz, Speyer and Worms became the center of Jewish life during medieval times. "This was a golden age as area bishops protected the Jews, resulting in increased trade and prosperity."