Al-Karkh or just Karkh is historically the name of the western half of Baghdad, Iraq, or alternatively, the western shore of the Tigris River as it ran through Baghdad. The eastern shore is known as al-Rusafa. Historically, al-Karkh has been a commerce market during the Abbasid Caliphate, located outside the main Round City due to safety concerns. It saw many exports and was the main business place for merchants and craftsmen. Al-Karkh has also historically suffered from infighting, fire, and floods that impacted its population and topography.

Baghdad is the capital of Iraq and the second-largest city in the Arab world after Cairo. It is located on the Tigris river. In 762 AD, Baghdad was chosen as the capital of the Abbasid Caliphate, and became its most notable major development project. Within a short time, the city evolved into a significant cultural, commercial, and intellectual center of the Muslim world. This, in addition to housing several key academic institutions, including the House of Wisdom, as well as a multi-ethnic and multi-religious environment, garnered it a worldwide reputation as the "Center of Learning".