Janet Kay Hagan was an American lawyer, banking executive, and politician who served as a United States Senator from North Carolina from 2009 to 2015. A member of the Democratic Party, she previously served in the North Carolina Senate from 1999 to 2009. By defeating Republican Elizabeth Dole in the 2008 election, she became the first woman to defeat an incumbent woman in a U.S. Senate election. She ran for reelection in 2014 but lost to Republican Thom Tillis, Speaker of the North Carolina House of Representatives, in a close race.

Mary Elizabeth Alexander Dole is an American attorney, author, and politician who served as a United States Senator from North Carolina from 2003 to 2009. A member of the Republican Party, she previously served in five presidential administrations, including as U.S. Secretary of Transportation under President Ronald Reagan from 1983 to 1987 and as U.S. Secretary of Labor under Reagan's successor, George H. W. Bush, from 1989 until 1990. Dole then left government to serve as president of the American Red Cross from 1991 to 1999; she departed from that position to seek the Republican nomination in the 2000 presidential election but eventually withdrew from the race.