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Khan Yunis

Khan Yunis is a city in the southern Gaza Strip. According to the Palestinian Central Bureau of Statistics, Khan Yunis had a population of 142,637 in 2007 and 202,000 in 2010 and 350,000 in 2012. Khan Yunis, which lies only 4 kilometers east of the Mediterranean Sea, has a semi-arid climate with temperature of 30 degrees Celsius maximum in summer and 10 degrees Celsius maximum in winter, with an annual rainfall of 260 mm; the Constituency of Khan Yunis had five members on the Palestinian Legislative Council. Following the 2006 Palestinian legislative election, there were three Hamas members, including Yunis al-Astal; the city is now under the Hamas administration of Gaza. Before the 14th century, Khan Yunis was a village known as "Salqah." To protect caravans and travelers a vast caravan serai was constructed there by the emir Yunus al-Noorzai Khan in 1387-88, a Turkic ruler. The growing town surrounding it was named "Khan Yunis" after him. In 1389 Yunus was killed in battle. Yunus ibn Abdallah an-Noorzai ad-Dawadar was the executive secretary, one of the high-ranking officials of the Mamluk sultan Barquq.

The town became an important center for trade and its weekly Thursday market drew traders from neighboring regions. The khan served as resting stop for couriers of the barid, the Mamluk postal network in Palestine and Syria. In late 1516 Khan Yunis was the site of a minor battle in which the Egypt-based Mamluks were defeated by Ottoman forces under the leadership of Sinan Pasha; the Ottoman sultan Selim I arrived in the area where he led the Ottoman army across the Sinai Peninsula to conquer Egypt. During the 17th and 18th centuries the Ottomans assigned an Azeban garrison associated with the Cairo Citadel to guard the fortress at Khan Yunis. Pierre Jacotin named the village Kan Jounes on his map from 1799, while in 1838, Robinson noted Khan Yunas as a Muslim village located in the Gaza district. In 1863 French explorer Victor Guérin visited Khan Yunis, he found it had about a thousand inhabitants, that many fruit trees apricots were planted in the vicinity. At the end of the 19th-century the Ottomans established a municipal council to administer the affairs of Khan Yunis, which had become the second largest town in the Gaza District after Gaza itself.

In the 1922 census of Palestine conducted by the British Mandate authorities, Khan Yunis had a population of 3890 inhabitants. In the 1945 statistics Khan Yunis had a population of 11,220, 11,180 Muslims and 40 Christians, with 2,302 and 53,820 dunams of land, according to an official land and population survey. Of this, 4,172 dunams were plantations and irrigable land, 23,656 used for cereals, while 1,847 dunams were built-up land. During the night of 31 August 1955, three Israeli paratroop companies attacked the British-built Tegart fort in Khan Yunis from where attacks had been carried out against Israelis; the police station, a petrol station and several buildings in the village of Abasan were destroyed, as well as railway tracks and telegraph poles. In heavy fighting, 72 Egyptian soldiers were killed. One Israeli soldier was killed and 17 were wounded; the operation led to a ceasefire on September 4, forcing President Gamal Abdel Nasser and the Egyptian government to halt Palestinian fedayeen operations against Israel.

One of the mechanized companies was commanded by Rafael Eitan. Before the Suez War, Khan Yunis was administered by the All-Palestine Government, seated in Gaza and in Cairo. After a fierce firefight, the Sherman tanks of the IDF 37th Armored Brigade broke through the fortified lines outside of Khan Yunis held by the 86th Palestinian Brigade, it was the only site in the Gaza strip where the Egyptian army put up any resistance to the Israeli invasion of Gaza, but it surrendered on 3 November 1956. There are conflicting reports of. Israel said that Palestinians were killed when Israeli forces were still facing armed resistance, while the Palestinians said all resistance had ceased by and that many unarmed civilians were killed as the Israel troops went through the town and camp, seeking men in possession of arms; the killings, dubbed the Khan Yunis massacre, were reported to the UN General Assembly on 15 December 1956 by the Director of the United Nations Relief and Works Agency, Henry Labouisse.

According to the report, the exact number of dead and wounded is not known, but the director received lists of names of persons killed from a trustworthy source, including 275 people, of which 140 were refugees and 135 local residents. After 1959, the All-Palestine Government of Gaza Strip was abolished and the city was included in the United Arab Republic, shortly disestablished and the Gaza Strip came under the direct Egyptian military occupation rule. In 1967, during the Six-Day War Israel occupied Khan Yunis again. Khan Yunis was the site of Israeli helicopter attacks in August 2001 and October 2002 that left several civilians killed, hundreds wounded and civilian buildings within the vicinity destroyed, it is known as a stronghold of Hamas. It is a status A territory. Khan Yunis is the second largest urban area in the Gaza Strip after Gaza City, it serves as the principal market center of the southern territory's southern half and hosts a weekly Bedouin souk involving local commodities. As of 2012 Khan Yunis had the highest unemployment rate in the Palestinian territories.

University College of Science and Technology Al Quds open univer

Oprozomib

Oprozomib is an orally active second-generation proteasome inhibitor developed by Proteolix, acquired by Onyx Pharmaceuticals, an Amgen subsidiary, in 2009. It selectively inhibits chymotrypsin-like activity of both the constitutive proteasome and immunoproteasome, it is being investigated for the treatment of hematologic malignancies multiple myeloma, with Phase 1b studies ongoing. Being an epoxyketone derivative, oprozomib is structurally related to carfilzomib and has the added benefit of being orally bioavailable. Like carfilzomib, it is active against bortezomib-resistant multiple myeloma cells. Oprozomib was granted orphan drug status for the treatment of Waldenström's macroglobulinaemia and multiple myeloma in 2014. Ixazomib — an orally available boronic acid-derived proteasome inhibitor approved for the treatment of multiple myeloma

Marcio Kogan

Marcio Kogan graduated from the School of Architecture and Urbanism at the University Presbyterian Mackenzie in 1976. He is the son of the engineer Aron Kogan, who became known in the 1950s and 1960s for the design and construction of large buildings in São Paulo, such as Edificio São Vito and Edificio Mirante do Vale. During the onset of his carecer, Marcio divided his time between cinema and architecture in partnership with Isay Weinfeld, his friend from university. In 1988, the duo produced a feature-film called “Fire and Passion”, between 1995 and 2004, they did 5 exhibitions together about architecture and humor. In 2001, Marcio Kogan's Office changed its name to Studio MK27 and since has gained greater international projection. Besides his working in Brazil, he is working on projects in Peru, Chile, United States, Spain, Switzerland, India and Indonesia. In 2011, Kogan was selected to be an Honorary Member of the American Institute of Architecture, for the entirety of his work, in a ceremony in New Orleans.

In 2012, Studio MK27 represented Brazil in the Venice Biennale of Architecture, in the exhibition at the national pavilion curated by Lauro Cavalcanti, who showed an outstanding Lúcio Costa installation. Kogan's projects are characterized by their architectural detail, formal simplicity, strong relations between the internal and external, great climactic comfort through passive sustainability, use of pure volumes and the application of traditional elements such as mashrabiyas and by designing a functional internal plan. Furthermore, he favors the use of raw materials such as wood and stone. In his projects there is always a reference to Brazilian modern architecture, of which Marcio has declared himself a great fan; the New York Times critic Paul Goldberger cited Kogan in 2013 as one of the main references of Brazilian Contemporary Architecture. During the first years of his career, the architectural projects were divided with Kogan's dedication to film-making. Between 1973 and 1979 he produced – together with Isay Weinfeld – 13 short films in Super 8, winning numerous awards in national festivals.

In 1983, the two made another short film, now in 35mm, “Idos com o Vento”, which received a prize at the Gramado Festival and at the Ibero-American Cine Huelva in Spain. Five years they launched their first and only long-feature and Passion, with a star-filled cast that included Mira Haar, Cristina Mutarelli, Carlos Moreno, Rita Lee and Fernanda Montenegro. All of their film productions had a strong relation with humor, above all through visual jokes, expressed by the interaction of the characters and the scenario. In Architecture, the principal projects of the onset of his career were the buildings of his office in 1977 – where he still maintains his activities – and Edificio Ljis, finished in 1980. Other than there solo projects, he did with Weinfeld the Goldfarb House in 1989, which brought references of Vila Arpel From the film My Uncle by Jacques Tati. During the 1990s, Kogan and Weinfeld designed the Metropolis Building, finished in 1996, the Hotel Fasano, one of the most important luxury hotels in São Paulo, headed by a traditional family of restaurateurs of the city.

Construction of Fasano started in 1996 and was completed in 2003. The partnership in film-making opened for exhibits about humor. Among the individual architectural projects developed in the 1990s, the outstanding ones are the Larmod Store and the Uma Store in Vila Madalena; the projects explored the internal spatiality with large ceiling-heights and minimized the use of materials and colors always done in white mortar. In 2001, Marcio Kogan's office became more collaborative and received a new name, Studio MK27; the work system adopted gave greater freedom as well as responsibility to the architects, who have now become co-authors of the projects, signing together with Kogan. In this organization, the task division was minimized and each architect accompanied all of the phases of the project, from the briefing with the client until the project delivery. In this phase, the Gama Issa House was published in international magazines. Highlights from these first years of Studio MK27 include Coser Photographic Studio – built within an industrial warehouse in the Cambuci neighborhood of São Paulo – and the Microbiology Museum at the Butantan Institute in São Paulo – a retrofit of an older structure, transformed into a center for didactic activities.

During the first decade of the 20th century, two of Studio MK27 houses won the Record House Award, promoted by the prestigious North-American magazine Architectural Record: the Du Plessis Home, which does a re-reading of the traditional elements of Brazilian architecture, such as veranda, the mashrabiyas and the patio, shortly thereafter BR House. For Micasa VolB, Studio MK27 returns with humor in architecture, this time in a commentary in Brazilian modernism; the project of this furniture store-showroom was defined in discussion on the work-site. The traditional exposed concrete was done randomly, building elements such as steel reinforcing bars were used as brises-soleil. Paraty House, concluded in 2009, received great attention from the specialized media, winning 10 international awards, including the Wallpaper* Design Award promoted to by the British magazine; this period is marked by the internationalization of Kogan's production and the diversification of the architectural programs. The ongoing projects include hotels in Portugal and Indonesia, projects being concluded in Chile and Uruguay.

In 2011, Kogan was selected t

Raymond Island

Raymond Island is a small island in the Gippsland Lakes in eastern Victoria, about 300 km from Melbourne. The island is 6 km long by 2 km wide, is just 200 m off the coast, across from the town of Paynesville; the island is named after William Odell Raymond a magistrate from New South Wales who established himself as a squatter in Gippsland in the 1840s. Raymond Island is well-known locally for its large koala population introduced to the island in 1953, for the Raymond Island Ferry, a chain ferry that links the island to Paynesville on the mainland; the Raymond Island Ferry provides the only link between the island and the mainland, but acts as an effective barrier to faster development of the island community. A ferry has run between Paynesville and Raymond Island since 1889, has been an integral and sometimes controversial feature of life on Raymond Island; some continue to call for the ferry to be replaced by a bridge. In 2011, the East Gippsland Shire Council is conducting another review of "Raymond Island Access", based on an action to "Develop a plan to resolve access to Raymond Island" in the Council Plan 2009-2013.

This follows earlier considerations. Before the current ferry, which runs on two chains, was commissioned in 1997, the topic was the subject of an academic paper in the Rural Society Journal which examined "the controversy over the proposal to link Raymond Island, Victoria to the mainland through construction of a bridge, to replace the current ferry service"; the issue has been discussed for decades without being permanently resolved, opinions remain divided about the relative merits of ferry versus bridge. The Raymond Island Community Association hosts regular meetings for residents and rate-payers, has roots that go back to 1949. RICA was formed in 2003 as an amalgamation of the Raymond Island Advancement League, started in 1949, Raymond Island Protection, formed in 1988; the Raymond Island Landcare Group formed in 1994 and covers 759 hectares. Its stated mission is to "protect and enhance the natural environment of Raymond Island by maintaining and protecting the natural attractions of the Island and development of low impact tourism infrastructure in harmony with maintaining the Island's character".

At one stage, thanks to the work of Reg Medling and Gordon Winch, Raymond Island had its own Bowling Green: Medwin Bowling Club. With the help of volunteers, a two rink Green was created on a vacant block of land, owned by Gordon and Beryl Winch, at 7-15 Eighth Avenue, just down from First Parade; the Green opened on 15 February 1987. Raymond Island had a Post Office from 3 April 1967 until 11 April 1968; the post office was run by Mrs. Annette Anderson, who operated it from a small hut at the back of her home; the post office closed. More long-lived was the Raymond Island primary school, which opened to students on 14 February 1902; the site of the school is on the corner of Gravelly Point Road and Centre Road, marked by a commemorative plaque. The first Head Teacher was Miss Jennifer Thompson. At one stage, student enrolments reached 41, but by 1912, enrolments had fallen to the point that the school closed down on 31 August; however just 18 months on 27 January 1914, the school reopened with an influx of new students.

Only 28 new enrolments were recorded between 1914 and 1934, leading the school to close for the final time in December 1934. After closing, the old school building was removed to Devon Road, where it became a private home. In 1897, Fred Barton held the first Presbyterian church service on Raymond Island, in a private home. Barton applied to the Lands Department for a church site soon after, obtained three acres on the corner of Gravelly Point Road and Centre Road, opposite what would become the school site. A bark hut was built on the site, services were held there until the church and Sunday School were removed to the newly built school in 1902. Raymond Island Community Website Raymond Island Ferry

Henry Wilkins (basketball)

Henry Robert Newell Wilkins is a British professional basketball player who plays for the Surrey Scorchers in the British Basketball League. Wilkins played for the Kingston Wildcats from U12 to U16, before spending two seasons with the London Towers. In 2007, Wilkins spent two seasons with the team, he helped the U18 team win their conference in his first year before being knocked out in the play-offs, led the team in scoring with an average of 26.4 points per game. The following year, he led the team with an average of 28.1 points per game as Richmond finished as league runner-up and reached the second round of the national play-offs. Playing with the men's team, he reached the national semi-finals of his division and was the leading scorer in the country with an average of 21.8 points per game. In 2010, Wilkins joined the Leeds Force of the National Basketball League. Playing 35 games, he averaged 9.4 points, 1.5 assists, 2.3 rebounds and 0.4 steals during his three seasons with the team. In 2013, he played 15 times in the Basketligaen.

Wilkins joined Villarrobledo in Spain a year before returning to England to join British Basketball League team the Surrey Scorchers for the 2015–16 season. After struggling for minutes, Wilkins returned to Spain to join Globalcaja Quintanar for the remainder of the season. Wilkins returned to semi-professional level for the 2016–17 season and joined Austrian team the Dornbirn Lions; the following year saw him move to Spain for a third time to join Tarragona, where he played 15 times. In September 2018, Wilkins rejoined the Surrey Scorchers

Battle of Farrukhabad

The Battle of Farrukhabad was an engagement during the Second Anglo-Maratha War between forces of the British East India Company and those of Maharaja Yashwantrao Holkar of the Maratha Empire. The battle took place at Farrukhabad in what is now India; the Company's forces, led by General Gerard Lake, surprised Holkar's forces after making forced marches of more than 60 miles in the preceding 24 hours. Lake "...attacked the Maratha camp where the soldiers were still sleeping off the effects of the previous night's revelry." Holkar himself narrowly escaped capture in the rout. Farrukhabad is one of the three tehsils in the Farrukhabad District of the State of Uttar Pradesh in northern India. Alison, Sir Archibald. History of Europe, Volume 11