King of the Four Corners of the World, alternatively translated as King of the Four Quarters of the World, King of the Heaven's Four Corners or King of the Four Corners of the Universe and often shortened to simply King of the Four Corners, was a title of great prestige claimed by powerful monarchs in ancient Mesopotamia. Though the term "four corners of the world" does refer to specific geographical places within and near Mesopotamia itself, these places were thought to represent locations near the actual edges of the world and as such, the title should be interpreted as something equivalent to "King of all the known world", a claim to universal rule over the entire world and everything within it.

The Akkadian Empire was the first known ancient empire of Mesopotamia, succeeding the long-lived civilization of Sumer. Centered on the city of Akkad and its surrounding region, the empire would unite Akkadian and Sumerian speakers under one rule and exercised significant influence across Mesopotamia, the Levant, and Anatolia, sending military expeditions as far south as Dilmun and Magan in the Arabian Peninsula.