L'ajo nell'imbarazzo is a melodramma giocoso, or opera, in two acts by Gaetano Donizetti. The Italian libretto was written by Jacopo Ferretti, after the 1807 play by Giovanni Giraud. At its premiere at the Teatro Valle, Rome, on 4 February 1824, it "was greeted with wild enthusiasm [and] it was with this opera that [...] Donizetti had his first really lasting success" During revisions planned for the 1826 production in Naples, Donizetti renamed the opera Don Gregorio, and it is under that name that most later productions were staged.

Domenico Gaetano Maria Donizetti was an Italian composer, best known for his almost 70 operas. Along with Gioachino Rossini and Vincenzo Bellini, he was a leading composer of the bel canto opera style during the first half of the nineteenth century and a probable influence on other composers such as Giuseppe Verdi. Donizetti was born in Bergamo in Lombardy. At an early age he was taken up by Simon Mayr who enrolled him with a full scholarship in a school which he had set up. There he received detailed musical training. Mayr was instrumental in obtaining a place for Donizetti at the Bologna Academy, where, at the age of 19, he wrote his first one-act opera, the comedy Il Pigmalione, which may never have been performed during his lifetime.