La Cisterna is a commune of Chile and census-designated city located in Santiago Province, Santiago Metropolitan Region. It was founded on 30 May 1925. It is part of Greater Santiago.

Santiago, also known as Santiago de Chile, is the capital and largest city of Chile and one of the largest cities in the Americas. It is located in the country's central valley and is the center of the Santiago Metropolitan Region, which has a population of seven million, representing 40% of Chile's total population. Most of the city is situated between 500–650 m (1,640–2,133 ft) above sea level.