Lake Okeechobee is the largest freshwater lake in the U.S. state of Florida. It is the tenth-largest natural freshwater lake among the 50 states of the United States and the second-largest natural freshwater lake contained entirely within the contiguous 48 states, after Lake Michigan.

The Kissimmee River is a river in south-central Florida, United States that forms the north part of the Everglades wetlands area. The river begins at East Lake Tohopekaliga south of Orlando, flowing south through Lake Kissimmee into the large, shallow Lake Okeechobee. Hurricane-related floods in 1947 prompted channelization of the meandering lower stretch, completed by 1970. The straightened course reduced wetland habitat and worsened pollution. In response, efforts since the 1990s have partially restored the river's original state and revitalized the ecosystem, as part of the broader restoration of the Everglades.