Lake and Peninsula Borough is a borough in the state of Alaska. As of the 2020 census, the population was 1,476, down from 1,631 in 2010. The borough seat of King Salmon is located in neighboring Bristol Bay Borough, although is not the seat of that borough. The most populous community in the borough is the census-designated place of Port Alsworth. With an average of 0.017 inhabitants per square kilometre, the Lake and Peninsula Borough is the second least densely populated organized county-equivalent in the United States; only the unorganized Yukon-Koyukuk Census Area has a lower density.

Becharof National Wildlife Refuge is a National Wildlife Refuge in the Aleutian Range of the Alaska Peninsula of southwestern Alaska. It is adjacent to Katmai National Park and Preserve. This national wildlife refuge, which covers an area of 1,200,000 acres (4,900 km2), was established in 1980 to conserve major brown bears, salmon, migratory birds, caribou, marine birds, and mammals and to comply with treaty obligations. It lies primarily in the east-central part of Lake and Peninsula Borough, but extends eastward into the mainland portion of Kodiak Island Borough. The refuge is administered from offices in King Salmon.