Landmark 81 is a supertall skyscraper in Ho Chi Minh City, Vietnam. It is primarily invested and developed by Vinhomes, the largest Vietnamese real-estate developer. Landmark 81 holds the position of the tallest building in Vietnam, the second tallest building in Southeast Asia, as well as the seventeenth tallest building in the world overall.

Ho Chi Minh City, commonly known as Saigon, is the most populous city in Vietnam, with a population of around 9.3 million in 2023. The city's geography is defined by rivers and canals, of which the eponymously-named Saigon River is the largest. As a municipality, Ho Chi Minh City consists of 16 urban districts, five rural districts, and one municipal city (sub-city). As the largest financial centre in Vietnam, Ho Chi Minh City has the highest gross regional domestic product out of all Vietnam provinces and municipalities, contributing around a quarter of the country's total GDP. Ho Chi Minh City's metropolitan area is ASEAN's 6th largest economy, also the biggest outside an ASEAN country capital.