Lee County is located in southwestern Florida, United States, on the Gulf Coast. As of the 2020 census, its population was 760,822. In 2022, the population was 822,453, making it the eighth-most populous county in the state. The county seat is Fort Myers, with a population of 86,395 as of the 2020 census, and the largest city is Cape Coral, with an estimated 2020 population of 194,016.

Southwest Florida is the region along the southwest Gulf coast of the U.S. state of Florida. The area is known for its beaches, subtropical landscape, and winter resort economy.