Leixões Sport Club, commonly known as Leixões, is a Portuguese sports club from Matosinhos. It is organised into several departments for many sports, such as athletics, boxing, football, futsal, handball, karate, swimming, volleyball, water polo and billiards. It is most well known for its professional football department. Its football department has hosted a B reserve team called Leixões S.C. B and also a C reserve team playing in lower leagues.

Matosinhos is a city and a municipality in the northern Porto district of Portugal, bordered in the south by the city of Porto. The population in 2011 was 175,478, and covered an area of approximately 62.42 square kilometres (24.10 sq mi). The urban centre, the city proper, had a population of 45,703 in 2001.