The Leo Frigo Memorial Bridge is a bridge on the north side of Green Bay, Wisconsin. It carries Interstate 43 over the Fox River just south of its mouth into Green Bay. Formerly known as the Tower Drive Bridge, it was renamed in 2002 "in recognition and appreciation of Leo Frigo, a civic and philanthropic leader in the Green Bay area. The bridge opened to traffic in 1981. Because of the bridge's height and slope, it is prone to being shut down during inclement weather. The bridge carries roughly 40,000 vehicles per day as of 2015.

Interstate 43 (I-43) is a 191.55-mile-long (308.27 km) Interstate Highway located entirely within the US state of Wisconsin, connecting I-39/I-90 in Beloit with Milwaukee and I-41, U.S. Highway 41 (US 41) and US 141 in Green Bay. State Trunk Highway 32 (WIS 32) runs concurrently with I-43 in two sections and I-94, I-894, US 10, US 41, US 45, and WIS 57 overlap I-43 once each. There are no auxiliary or business routes connected to I-43, though an alternate route to direct traffic during road closures is signed along local and state highways from Milwaukee County north into Brown County.