The Louise M. Slaughter Rochester Station is an Amtrak intermodal transit station in Rochester, New York. Local and regional bus transportation is provided by the Rochester-Genesee Regional Transportation Authority. Various taxi firms service the station, as well. The station is located on the north side of Rochester, just east of High Falls on the south side of the tracks.

The Lake Shore Limited is an overnight passenger train operated by Amtrak between Chicago and the Northeastern United States, with sections to New York City and Boston. The central segment of the route runs along the southern shore of Lake Erie.