The Lower East Side, sometimes abbreviated as LES, is a historic neighborhood in the southeastern part of Manhattan in New York City. It is located roughly between the Bowery and the East River from Canal to Houston streets. Historically, it was understood to encompass a much larger area, from Broadway to the East River and from East 14th Street to Fulton and Franklin Streets.

New York's 12th congressional district is a congressional district for the United States House of Representatives located in New York City. As of 2023, it is represented by Democrat Jerry Nadler, redistricted incumbent of the former 10th congressional district who defeated incumbent Carolyn Maloney in the August 2022 Democratic primary. The redrawn District 12 includes the Upper West Side constituency represented by Nadler since the 1990s, the Upper East Side, and all of Midtown Manhattan. The district is the smallest congressional district by area in the U.S. The 12th district's per capita income, in excess of $75,000, is the highest among all congressional districts in the United States.