Lucrezia Maria Romola de' Medici was an Italian noblewoman, the eldest daughter of Lorenzo de' Medici and Clarice Orsini and mother of Maria Salviati and Giovanni Salviati. Her portrait was considered as the baby Jesus in Our Lady of the Magnificat of Sandro Botticelli.

Lorenzo di Piero de' Medici, known as Lorenzo the Magnificent, was an Italian statesman, the de facto ruler of the Florentine Republic, and the most powerful patron of Renaissance culture in Italy. Lorenzo held the balance of power within the Italic League, an alliance of states that stabilized political conditions on the Italian Peninsula for decades, and his life coincided with the mature phase of the Italian Renaissance and the golden age of Florence. As a patron, he is best known for his sponsorship of artists such as Botticelli and Michelangelo. On the foreign policy front, Lorenzo manifested a clear plan to stem the territorial ambitions of Pope Sixtus IV, in the name of the balance of the Italic League of 1454. For these reasons, Lorenzo was the subject of the Pazzi conspiracy (1478), in which his brother Giuliano was assassinated. The Peace of Lodi of 1454 that he supported among the various Italian states collapsed with his death. He is buried in the Medici Chapel in Florence.