Mackinaw City is a village at the northernmost point of the Lower Peninsula of Michigan, United States. Divided between Cheboygan and Emmet counties, Mackinaw City is located at the southern end of the Mackinac Bridge, which carries Interstate 75 over the Straits of Mackinac to the Upper Peninsula. Mackinaw City, along with St. Ignace, serves as an access point to Mackinac Island. For these reasons, Mackinaw City is considered one of Michigan's most popular tourist attractions.

Interstate 75 (I-75) is a part of the Interstate Highway System that runs north–south from Miami, Florida, to Sault Ste. Marie in the Upper Peninsula of the US state of Michigan. I-75 enters the state from Ohio in the south, north of Toledo, and runs generally northward through Detroit, Pontiac and Bay City, crosses the Mackinac Bridge, and ends at the Canadian border in Sault Ste. Marie. The freeway runs for approximately 396 miles (637 km) on both of Michigan's major peninsulas. The landscapes traversed by I-75 include Southern Michigan farmland, northern forests, suburban bedroom communities, and the urban core of Detroit. The freeway also uses three of the state's monumental bridges to cross major bodies of water. There are four auxiliary Interstates in the state related to I-75, as well as nine current or former business routes, with either Business Loop I-75 or Business Spur I-75 designations.