Macy's Herald Square is the flagship of Macy's department store, as well as the Macy's, Inc. corporate headquarters, on Herald Square in Manhattan, New York City. The building's 2.5 million square feet (230,000 m2), which includes 1.25 million square feet (116,000 m2) of retail space, makes it the largest department store in the United States and among the largest in the world. The store has an in-store jail, Room 140, where customers suspected of shoplifting are detained.

Sixth Avenue – also known as Avenue of the Americas, although this name is seldom used by New Yorkers – is a major thoroughfare in New York City's borough of Manhattan, on which traffic runs northbound, or "uptown". It is commercial for much of its length.