Maine Medical Center is a 700-licensed-bed teaching hospital in Portland, Maine, United States. Affiliated with Tufts University School of Medicine, it is located in the Western Promenade neighborhood. It has a staff of over 9,500. The facility is one of only three Level I Trauma Centers in Northern New England. Founded in 1874, it is the largest hospital in northern New England with 28,000 inpatient visits, about 500,000 outpatient visits, 88,000 emergency visits, and over 27,000 surgeries performed annually. MMC is structured as a non-profit, private corporation governed by volunteer trustees. Maine Medical Center is wholly owned by, and serves as the flagship hospital for, MaineHealth, a non-profit healthcare network servicing Maine and New Hampshire.

The Tufts University School of Medicine is the medical school of Tufts University, a private research university in Massachusetts. It was established in 1893 and is located on the university's health sciences campus in downtown Boston. It has clinical affiliations with numerous doctors and researchers in the United States and around the world, as well as with its affiliated hospitals in both Massachusetts, and Maine.