Malden is a city in the northeast corner of Dunklin County, Missouri, United States, located near the intersection of Missouri Route 25 and U.S. Route 62. The population was 4,277 at the 2010 census. Malden is within Missouri's 8th congressional district.

Dunklin County is located in the Bootheel of the U.S. state of Missouri. As of the 2020 census, the population was 28,283. The largest city and county seat is Kennett. The county was officially organized on February 14, 1845, and is named in honor of Daniel Dunklin, a Governor of Missouri who died the year before the county was organized.