Manslaughter is a 1922 American silent drama film directed by Cecil B. DeMille and starring Thomas Meighan, Leatrice Joy, and Lois Wilson. It was scripted by Jeanie MacPherson adapted from the novel of the same name by Alice Duer Miller. Art direction and costumes for the film were done by Paul Iribe.

Cecil Blount DeMille was an American filmmaker and actor. Between 1914 and 1958, he made 70 features, both silent and sound films. He is acknowledged as a founding father of American cinema and the most commercially successful producer-director in film history. His films were distinguished by their epic scale and by his cinematic showmanship. His silent films included social dramas, comedies, Westerns, farces, morality plays, and historical pageants. He was an active Freemason and member of Prince of Orange Lodge #16 in New York City.