The Manufacturers Trust Company Building, also known as 510 Fifth Avenue, is a commercial building at the southwest corner of West 43rd Street and Fifth Avenue in Midtown Manhattan, New York City. Opened in 1954, it is the first bank building in the United States to be built in the International Style. Charles Evans Hughes III and Gordon Bunshaft of Skidmore, Owings & Merrill (SOM) designed the building, along with Roy O. Allen and project manager Patricia W. Swan. The interior was designed by Eleanor H. Le Maire, while Harry Bertoia was hired as an artist for some of the building's artwork. 510 Fifth Avenue was built as a bank for the Manufacturers Trust Company, whose president Horace C. Flanigan wanted the design to be inviting to customers.

Gordon Bunshaft was an American architect, a leading proponent of modern design in the mid-twentieth century. A partner in Skidmore, Owings & Merrill (SOM), Bunshaft joined the firm in 1937 and remained with it for more than 40 years. His notable buildings include Lever House in New York, the Beinecke Rare Book and Manuscript Library at Yale University, the Hirshhorn Museum and Sculpture Garden in Washington, D.C., the National Commercial Bank in Jeddah, Saudi Arabia, 140 Broadway, and Manufacturers Hanover Trust Branch Bank in New York.