Margarita María Cedeño Lizardo, formerly known as Margarita Cedeño de Fernández, is a Dominican politician who served as Vice President of the Dominican Republic from 2012 to 2020. She was married to former president, Leonel Fernández and served as the First Lady of the Dominican Republic from 2004 to 2012.

The vice president of the Dominican Republic is the second-highest political position in the Dominican Republic. The vice president is the first person in the presidential line of succession, ascending to the presidency upon the death, resignation, or removal of the president. There have been thirty-nine vice presidents of the Dominican Republic. Under the Constitution of the Dominican Republic, the vice president shall be elected along with the president.