Mari was an ancient Semitic city-state in modern-day Syria. Its remains form a tell 11 kilometers north-west of Abu Kamal on the Euphrates River western bank, some 120 kilometers southeast of Deir ez-Zor. It flourished as a trade center and hegemonic state between 2900 BC and 1759 BC. The city was built in the middle of the Euphrates trade routes between Sumer in the south and the Eblaite kingdom and the Levant in the west.

Deir ez-Zor is the largest city in eastern Syria and the seventh largest in the country. Located on the banks of the Euphrates River 450 km (280 mi) to the northeast of the capital Damascus, Deir ez-Zor is the capital of the Deir ez-Zor Governorate. In the 2018 census, it had a population of 271,800.