Marvel Team-Up is an American comic book series published by Marvel Comics. The series featured two or more Marvel characters in one story. The series was originally published from March 1972 through February 1985, and featured Spider-Man as the lead "team-up" character in all but ten of its 150 issues, and in six of its seven Annuals. It was the first major ongoing spin-off series for Spider-Man, being preceded only by the short-lived The Spectacular Spider-Man magazine. Of the issues that did not star Spider-Man, the Human Torch headlines six issues ; the Hulk, four ; and Aunt May, one (#137). Publication of most of the issues starring the Human Torch coincided with that of Giant-Size Spider-Man, an alternate Spider-Man "team-up"-themed series by the regular Marvel Team-Up creative team. When cancelled with #150 in 1985, the title was replaced by Web of Spider-Man.

Spider-Man is a superhero appearing in American comic books published by Marvel Comics. Created by writer-editor Stan Lee and artist Steve Ditko, he first appeared in the anthology comic book Amazing Fantasy #15 in the Silver Age of Comic Books. He has been featured in comic books, television shows, films, video games, novels, and plays.