Mary, Scherrie & Susaye is the twenty-ninth and final studio album by The Supremes, released in 1976 on the Motown label. It featured the final line-up for the Supremes, composed of original Supreme Mary Wilson and latter-day members Scherrie Payne and Susaye Greene. All three Supremes take leads on the album. The album was a mixture of disco dance tracks (Hi-NRG) and R&B ballads. Payne and Greene mostly took over the dance tracks while Wilson performed the ballads. The album was released in October 1976, nine months before the trio disbanded.

The Supremes were an American girl group and a premier act of Motown Records during the 1960s. Founded as the Primettes in Detroit, Michigan, in 1959, the Supremes were the most commercially successful of Motown's acts and the most successful American vocal band, with 12 number-one singles on the Billboard Hot 100. Most of these hits were written and produced by Motown's main songwriting and production team, Holland–Dozier–Holland. It is said that their breakthrough made it possible for future African-American R&B and soul musicians to find mainstream success. Billboard ranked the Supremes as the 16th greatest Hot 100 artist of all time.