Maryland Route 85 is a state highway in the U.S. state of Maryland. Known as Buckeystown Pike, the state highway runs 10.80 miles (17.38 km) from MD 28 in Tuscarora north to the Frederick city limit north of Interstate 70 (I-70), where the highway continues north as East Street. MD 85 connects Tuscarora and Buckeystown in southern Frederick County with the county seat of Frederick. The state highway also links the suburban area between Buckeystown and Frederick with I-70 and I-270. MD 85 is the old alignment of U.S. Route 15, which was originally constructed between Tuscarora and Frederick in the late 1910s and early 1920s. MD 85 was assigned to the highway in 1970 when US 15 was moved to a new highway heading north from its Potomac River crossing at Point of Rocks. The state highway was extended north to the city of Frederick as part of a project to overhaul MD 355's interchange with I-70 in the first decade of the 21st century.

Interstate 70 (I-70) is a part of the Interstate Highway System that runs from Cove Fort, Utah, to Woodlawn just outside of Baltimore, Maryland. In Maryland, the Interstate Highway runs 91.85 miles (147.82 km) from the Pennsylvania state line in Hancock east to the Interstate's eastern terminus at its junction with I-695. I-70 is the primary east–west Interstate in Maryland; the Interstate Highway connects Baltimore—and Washington, D.C., via I-270—with Western Maryland. The Interstate serves Frederick and Hagerstown directly and provides access to Cumberland via its junction with I-68 at Hancock. I-70 runs concurrently with its predecessor highway, U.S. Route 40 (US 40), from Hancock to Indian Springs in Washington County and from Frederick to West Friendship in Howard County.