The General Society of Mayflower Descendants — commonly called the Mayflower Society — is a hereditary organization of individuals who have documented their descent from at least one of the 102 passengers who arrived on the Mayflower in 1620 at what is now Plymouth, Massachusetts. The Society was founded at Plymouth in 1897.

Mayflower was an English sailing ship that transported a group of English families, known today as the Pilgrims, from England to the New World in 1620. After 10 weeks at sea, Mayflower, with 102 passengers and a crew of about 30, reached what is today the United States, dropping anchor near the tip of Cape Cod, Massachusetts, on November 21 [O.S. November 11], 1620.