The post of Mayor of the City of New Orleans has been held by the following individuals since New Orleans came under American administration following the Louisiana Purchase — the 1803 acquisition by the U.S. of 828,800 square miles (2,147,000 km2) of the French province La Louisiane. In all mayoral elections since 1930, New Orleans has used a two-round system with a preliminary round and a runoff if no candidate reached a majority in the first round. All mayors of New Orleans since 1872 have been Democrats.

LaToya Cantrell is a politician serving as the Mayor of New Orleans, Louisiana since May 7, 2018. A Democrat, Cantrell is the first woman to hold the office. Before becoming mayor, Cantrell represented District B on the New Orleans City Council from 2012 to 2018.