McCarthy is a census-designated place (CDP) in Copper River Census Area, Alaska, United States. It is in Wrangell-St. Elias National Park and Preserve. The population was 107 at the 2020 census, up from 28 in 2010.

Wrangell–St. Elias National Park and Preserve is an American national park and preserve managed by the National Park Service in south central Alaska. The park and preserve were established in 1980 by the Alaska National Interest Lands Conservation Act. The protected areas are included in an International Biosphere Reserve and are part of the Kluane/Wrangell–St. Elias/Glacier Bay/Tatshenshini-Alsek UNESCO World Heritage Site. The park and preserve form the largest area managed by the National Park Service with a total of 13,175,799.07 acres, an expanse larger than nine U.S. states and around the same size as Bosnia and Herzegovina or Croatia. 8,323,147.59 acres are designated as the national park, and the remaining 4,852,652.14 acres are designated as the preserve. The area designated as the national park alone is larger than the 47 smallest American national parks combined and is more than twice the size of all but two other national parks. Its area makes up over 15% of all national park designated land in the United States.