The Medicine Bow Mountains are a mountain range in the Rocky Mountains that extend 100 miles (160 km) from northern Colorado into southern Wyoming. The northern extent of this range is the sub-range the Snowy Range. From the northern end of Colorado's Never Summer Mountains, the Medicine Bow mountains extend north from Cameron Pass along the border between Larimer and Jackson counties in Colorado and northward into south central Wyoming. In Wyoming, the range sits west of Laramie, in Albany and Carbon counties to the route of the Union Pacific Railroad and U.S. Interstate 80. The mountains often serve as a symbol for the city of Laramie. The range is home to Snowy Range Ski Area.

Wyoming is a landlocked state in the Mountain West subregion of the Western United States. It borders Montana to the north and northwest, South Dakota and Nebraska to the east, Idaho to the west, Utah to the southwest, and Colorado to the south. With a population of 576,851 in 2020, Wyoming is the least populous state despite being the 10th largest by area, with the second-lowest population density after Alaska. The state capital and most populous city is Cheyenne, which had a population of 65,132 in 2020.