The Melbourne to Warrnambool Classic cycling race is a one-day road bicycle race. The race started in 1895 and is Australia's oldest one day race and the world's second oldest one day race, after the Liège–Bastogne–Liège Classic. Historically until 1938 the race started in Warrnambool and finished 165 miles (266 km) later in Melbourne. In 1895 the race was run in the opposite direction, from Melbourne to Warrnambool and then again from 1939. The route started in the Melbourne central business district and followed the Princes Highway to Warrnambool on Victoria's western coast. This traditional route was the longest race on the Union Cycliste Internationale (UCI) calendar, the exact distance varying slightly over time.

Warrnambool is a city on the south-western coast of Victoria, Australia. At the 2021 census, Warrnambool had a population of 35,743. Situated on the Princes Highway, Warrnambool (Allansford) marks the western end of the Great Ocean Road and the southern end of the Hopkins Highway.