Mesoamerica is a historical region and cultural area that begins in the southern part of North America and extends to the Pacific coast of Central America, thus comprising the lands of central and southern Mexico, all of Belize, Guatemala, El Salvador, and small parts of Honduras, Nicaragua and Costa Rica. As a cultural area, Mesoamerica is defined by a mosaic of cultural traits developed and shared by its indigenous cultures.

In anthropology and geography, a cultural area, cultural region, cultural sphere, or culture area refers to a geography with one relatively homogeneous human activity or complex of activities (culture). Such activities are often associated with an ethnolinguistic group and with the territory it inhabits. Specific cultures often do not limit their geographic coverage to the borders of a nation state, or to smaller subdivisions of a state.