A metalloproteinase, or metalloprotease, is any protease enzyme whose catalytic mechanism involves a metal. An example is ADAM12 which plays a significant role in the fusion of muscle cells during embryo development, in a process known as myogenesis.
Metalloproteinase
Myogenesis is the formation of skeletal muscular tissue, particularly during embryonic development.
Myoblasts (cells with a single nucleus, represented in violet) fusing together to form muscle fibers (multinucleated muscle cells) during myogenesis
Patient with Waardenburg syndrome III (Waardenburg Klein Syndrome) with wide-set eyes.
Muscular Dystrophy Histopathology.