The Midland Highway is one of Tasmania's major inter-city highways, running for 176 kilometres (109 mi) between Hobart and Launceston. It is part of the AusLink National Network and is a vital link for road freight to transport goods to and from the two cities. It represents a major north–south transportation corridor in Tasmania and has the route 1 designation as part of the National Highway. The highway consists of various traffic lane arrangements, the most common being two lanes – one in each direction, with overtaking options and at-grade intersections. At both the Launceston and Hobart sections of the highway there are small portions of grade-separated dual carriageway.

Launceston is a city in the north of Tasmania, Australia, at the confluence of the North Esk and South Esk rivers where they become the Tamar River (kanamaluka). As of 2021, the Launceston urban area has a population of 90,953. Launceston is the second most populous city in Tasmania after the state capital, Hobart. As of 2020, Launceston is the 18th largest city in Australia. Launceston is the fifth-largest inland city and the ninth-largest non-capital city in Australia. Launceston is regarded as the most livable regional city, and was one of the most popular regional cities to move to in Australia from 2020 to 2021. Launceston was named Australian Town of the Year in 2022.